Fast Food Restaurant – illustrative photo

Fast Food RestaurantSouth San Francisco, CA

McDonald's – 381 South Airport Boulevard, South San Francisco

Open now · closes 10:00 PM

Directions Call

Illustrative photo

Opening hours

Open now · closes 10:00 PM

Weekly opening hours of McDonald's
Monday	5:00 AM – 10:00 PM
Tuesday	5:00 AM – 10:00 PM
Wednesday	5:00 AM – 10:00 PM
Thursday	5:00 AM – 10:00 PM
Friday	5:00 AM – 10:00 PM
Saturday	5:00 AM – 10:00 PM
Sunday	5:00 AM – 10:00 PM

Local time in South San Francisco: 9:11 PM (PDT). Holiday hours may differ – call (650) 871-6018 to confirm.

Location & directions

Tap for directions

381 South Airport Boulevard
South San Francisco, CA 94080

Google Maps Apple Maps Waze

About McDonald's

Located at 381 South Airport Boulevard in South San Francisco, California, McDonald's is a fast food restaurant. It is one of 56 places to eat and drink we list in South San Francisco.

McDonald's is open daily, 5:00 AM – 10:00 PM.

Service options include takeout and drive-through. On the menu: burgers.

For questions or orders, call (650) 871-6018.

Quick facts

Category: Fast Food Restaurant · Burger
Address: 381 South Airport Boulevard, South San Francisco, CA 94080
Phone: (650) 871-6018
Hours: Open daily, 5:00 AM – 10:00 PM
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for fast food restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Takeout
Drive-through

Amenities

Wi-Fi

Reviews

Write a review

No visitor reviews yet. Been to McDonald's? Share your experience to help other diners.

Frequently asked questions

What are McDonald's's opening hours?

Open daily, 5:00 AM – 10:00 PM. Monday: 5:00 AM – 10:00 PM; Tuesday: 5:00 AM – 10:00 PM; Wednesday: 5:00 AM – 10:00 PM; Thursday: 5:00 AM – 10:00 PM; Friday: 5:00 AM – 10:00 PM; Saturday: 5:00 AM – 10:00 PM; Sunday: 5:00 AM – 10:00 PM.

Is McDonald's open on Sunday?

Yes, McDonald's is open on Sundays: 5:00 AM – 10:00 PM.

Where is McDonald's located?

McDonald's is located at 381 South Airport Boulevard, South San Francisco, CA 94080.

What is the phone number of McDonald's?

You can call McDonald's at (650) 871-6018.

Does McDonald's offer delivery or takeout?

Delivery is not listed for McDonald's, and takeout is available. Listed service options: takeout and drive-through.